An Evidence Integration Lab Initiative

BIOSTATISTICS-DEMYSTIFIED

Interactive calculators for Biostatistics for Clinicians — one chapter, one concept, one clinical analogy at a time.

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Disclaimer: This calculator is intended for educational purposes only. Results are provided to support statistical learning and should not be used as the sole basis for clinical decision-making. Always interpret statistical outputs in the context of study design, clinical relevance, and professional judgement. An Evidence Integration Lab Initiative.

Chapter Calculators

2

Central Tendency & Dispersion

Mean · Median · Mode · Range · IQR · SD · SE

Enter any numerical dataset and instantly calculate all measures of central tendency and dispersion. Each result includes a plain-language explanation and a clinical nephrology example. Detects skewness and tells you what to report.

Analogy: eGFR in a CKD clinicNow you'll notice.
3

P-value & Confidence Intervals

One-sample t-test · Two-sample comparison · Proportion CI

Calculate p-values and 95% confidence intervals from your data. The app explains what the p-value actually measures, what the CI tells you that the p-value does not, and how to distinguish statistical from clinical significance.

Analogy: Renal biopsy — absence of evidenceNow you'll question.
4

Effect Size, Power & NNT

ARR · RRR · NNT · Cohen's d · Power · Sample Size

From statistical significance to clinical meaning. Calculate ARR, RRR, NNT, and NNH for binary outcomes; Cohen's d for continuous outcomes; and statistical power and required sample size for study planning.

Analogy: DAPA-CKD journal club — how many patients do I treat?Now you'll choose.
5

Composite Outcome Dissector

ARR per component · Dominance · Red flags · Direction consistency

Enter each component of a composite endpoint, label it hard or soft, and see exactly what drove the trial result. Flags direction inconsistency, soft-endpoint dominance, and hard endpoints trending the wrong way.

Analogy: The trial was positive — but which component moved?Now you'll dissect.

How to use this app

Each calculator corresponds to a chapter in Biostatistics for Clinicians. Open the relevant chapter, read the clinical analogy, then come here to enter your own data and see the concept in action. The DIY pages at the end of each chapter contain practice datasets you can load directly with one click.

Every result has an Explain button. Tap it to read the plain-language definition, a clinical example from nephrology practice, and guidance on when that measure should and should not be used. Use the Download Report button to export a formatted summary with the full interpretation.